Research

Current and recent funding for applied malaria research and evaluation

The faculty within the Center for Applied Malaria Research and Evaluation have established a solid track record in funding, with over US$5 million in funding from the Bill & Melinda Gates Foundation, NIH, CDC, USAID and the World Bank, in countries including Haiti, Zambia, Ethiopia, Benin, Ghana, Mali, Senegal, the Gambia and Eritrea.  Current and recent funding in applied malaria research supporting faculty within the Center includes:

Ongoing projects:

Malaria Elimination in Haiti (Malaria Zero – http://www.malariazeroalliance.org/)
Funder: Bill & Melinda Gates Foundation
Dates: 1/2015 – present
Locations: Haiti and the Dominican Republic
Project description: CAMRE, as part of the Malaria Zero consortium, has received a 6-year $30 million grant from the Bill& Melinda Gates Foundation focused on eliminating malaria from Haiti. The Malaria Zero consortium consists of Tulane-CAMRE, the CDC, the London School of Hygiene and Tropical Medicine, the Clinton Health Access Initiative, the Carter Center, PAHO, the Haitian Ministère de la Santé Publique et de la Population, and the CDC Foundation. CAMRE-Tulane is responsible for leading operations research and the evaluation of malaria transmission interruption within HaMEC.

VectorWorks
Funder: USAID
Dates: 1/2015 – present
Locations: Global
Project description: CAMRE has also recently won an award as a partner on the VectorWorks project, a $30 Million award from USAID to fund a partnership between Johns Hopkins Center for Communication Programs, Population Services International, the Mennonite Economic Development Agency, Tropical Health LLP, the Swiss Tropical and Public Health Institute and the Tulane University School of Public Health and Tropical Medicine to support the development and deployment of new and existing vector control interventions for malaria.

Malaria Elimination in Zambia
Funder: Bill & Melinda Gates Foundation via PATH
Dates: 1/2014 –present
Locations: Zambia
Project description: The focus of this project is to assess the impact of a mass drug administration (MDA) strategy using dihydroartemisinin + piperaquine (DHAp) to eliminate malaria in southern Province Zambia using a community randomized controlled trial (CRCT). Sub-studies imbedded within the larger overall impact evaluation include quantifying the population coverage of the MDA interventions; identification of systematic barriers to achieving high coverage; assessing and comparing the cost and cost-effectiveness of MDA with DHAp to no mass treatment; assessing the adherence of taking a full course of DHAp by the MDA interventions; assessing the clearance of asexual stage parasites at day 7 following the administration of DHAp; and assessing the acceptability of participating in the MDA interventions among community members and health care leaders.

Strengthening Malaria Monitoring and Evaluation Systems (SMMES) in Ethiopia
Funder: USAID-Ethiopia
Dates: 10/2013 – present
Locations: Ethiopia
Project description: The focus of this 5-year project is to support malaria epidemic detection in Ethiopia, in addition to providing technical support to the Federal Ministry of Health for malaria prevention and control. This project is being done in collaboration with Addis Continental Institute of Public Health and the President’s Malaria Initiative.

International Center for Excellence in Malaria Research (ICEMR)
Funder: NIH
Dates: 9/2010 – present
Locations: Senegal, Gambia, Mali
Project description: This 7-year peer-reviewed umbrella research grant assesses epidemiological and entomological dynamics related to malaria transmission, genetic diversity, prevention and control at 4 sites in The Gambia, Mali, and Senegal.

 

Completed projects:

Collaboration on malaria research with PATH-Malaria Control and Evaluation Partnership in Africa (MACEPA)
Funder: Bill & Melinda Gates Foundation via PATH
Dates: 4/2010 – 12/2013
Locations: Zambia, Ethiopia, Tanzania and Senegal
Project description: The focus of this project is to support the MACEPA project in malaria M&E and operations research, including the following: measuring / modeling malaria transmission; malaria epidemiology; measuring malaria intervention coverage; evaluation of Mass Screen and Treat intervention; evaluating impact of national program in Zambia; capacity development in malaria epidemiology, sampling and program evaluation; participation in RBM Monitoring and Evaluation Reference Group; and participation in the WHO Child Health Epidemiology Reference Group.

Ethiopia malaria surveillance (Ethiopia Associate Award)
Funder: USAID-Ethiopia
Dates: 09/2009 – 10/2013
Locations: Ethiopia
Project description: The focus of this project has been to develop an SMS reporting system for collecting malaria case data at 85 health centers and posts, supporting PMI Ethiopia malaria impact evaluation, developing a malaria data reporting system, strengthening capacity at health centers and posts to record and report malaria epidemics in Oromia, and contributing to the evidence base of how travel relates to malaria infection.

Lives Saved Tool (LiST) modeling for the Child Health Epidemiology Reference Group
Funder: BMGF via UNICEF USA Fund
Dates: 6/2008 – 03/2013
Project description: Project focused on the review, development and maintenance of estimates of impact of intervention on malaria mortality in Africa.

Improving Malaria Diagnostics (IMAD) sub-agreement
Funder: USAID
Dates: 09/2011 – 04/2013
Locations: Ghana and Benin
Project description: The project focused assessing diagnostic capacity in PMI countries, with Tulane focusing on the following malaria activities under the IMAD impact evaluation: data collection, training and implementation within selected health facilities; development of survey instruments; and data analysis.

Translating efficacy into effectiveness of insecticide-treated nets (ITNs) using an interpersonal communication intervention to decrease the gap between ITN ownership and use
Funder: CDC- R18CK000102-01
Dates: 10/2007 – 9/2011
Locations: Zambia
Project description: The long-term goal of the project was to provide public health scientists and officials with an effective intervention to optimize ITN uptake and use among children and pregnant women as they become more widely available through the scale-up of national distribution programs. It is hypothesized that a village-based interpersonal communication (IPC) intervention will increase ITN use among households already possessing them within the context of a national ITN distribution program currently underway in Zambia. The focus of this project was to: 1) test if a village-based IPC intervention increases the proportion of children using ITNs within households possessing them within the context of a large-scale ITN distribution program in the Luangwa District of Zambia; 2) determine the costs associated with achieving such increased ITN use; and 3) identify household, community and policy-level factors that facilitate or impede ITN use among children.

Planning malaria training in Zambia
Funder: NIH Fogarty International Center- D71TW008280-01
Dates: 7/2009 – 6/2010
Locations: Zambia
Project description: The focus of this project was to plan a five year program for providing integrated research training to Zambian scientists and health professionals in malaria control research.

Impact evaluation of indoor residual spray campaign in Eritrea
Funder: World Bank
Dates: 09/2009 – 10/2010
Locations: Eritrea
Project description: Study focused on the design and implementation of an impact evaluation, data collection training, participation in the development of survey instruments, development of data sets, and analysis of impact evaluation data.

Measuring malaria transmission in Haiti
Funder: USAID-Haiti
Dates: 8/2006 – 03/2007
Locations: Haiti
Project description: The specific aim of this project was to obtain population-based data on the burden of malaria within the Artibonite Valley of Haiti to help guide public health strategies to control malaria and measure results.